Quaternary ammonium salts
Medchemexpress LLC Cholic acid 7-sulfate (7-Sulfocholic acid) | 60320-05-0 | 99.9% | 50 MG
Cholic acid 7-sulfate is a selective agonist targeting TGR5 (EC50=0.17 μM) and a ligand for MHC class I-related protein (MR1). As a gut-restricted TGR5 agonist, it binds to TGR5 on enteroendocrine L cells, induces GLP-1 secretion, and improves glucose tolerance in a TGR5-dependent manner. It also acts as an endogenous ligand for MR1, promoting the survival of mucosal-associated invariant T cells (MAIT) and the expression of homeostatic gene signatures, affecting MAIT cell development and function. It is mainly used in the research of diabetes and MAIT cell-related immune regulation.
- Selective agonist targeting TGR5 (EC50=0.17 μM).
- Ligand for MHC class I-related protein (MR1).
- Binds to TGR5 on enteroendocrine L cells.
- Induces GLP-1 secretion and improves glucose tolerance.
- Promotes survival of mucosal-associated invariant T cells (MAIT).
- Used in research of diabetes and MAIT cell-related immune regulation.
Medchemexpress LLC Choline Fenofibrate | 856676-23-8 | 99.5% | 421.91 | 1 ML
Choline Fenofibrate is a choline salt of Fenofibric acid that releases free Fenofibric acid in the gastrointestinal tract. Fenofibric acid acts as a peroxisome proliferator-activated receptor (PPAR) activator with an antihyperlipidemic effect.
- Acts as a PPAR activator
- Demonstrates antihyperlipidemic effects
- Exhibits excellent oral bioavailability
- High Cmax after oral administration
- Has a terminal elimination half-life suitable for in vivo studies
Medchemexpress LLC Choline theophyllinate (Oxtriphylline) | 4499-40-5 | 99.95% | 50 MG
Choline theophyllinate (Oxtriphylline) is a choline salt of theophylline with anti-asthmatic activity. It is intended for research use only.
- Anti-asthmatic activity
- For research use only
Medchemexpress LLC Cholic acid impurity 1 | 24637-46-5 | 95.1% | 390.6 g/mol | C24H38O4 | 10 MG
Cholic acid impurity 1 is a defined impurity of cholic acid provided as a solid reference material for laboratory research. It is supplied in milligram quantities for analytical reference, impurity profiling, and characterization of synthetic intermediates.
- Offered as a powder suitable for analytical applications.
- CAS number 24637-46-5.
- Molecular formula C24H38O4; molecular weight 390.6 g/mol.
- Typical purity ~95.1%.
- Packaged in milligram quantities; recommended storage: powder at -20°C, in solution at -80°C.
- For research use only; not for clinical or human use.
Chem-Impex International, Inc. Choline chloride | 67-48-1 | MFCD00011721 | 10KG
Choline chloride, 67-48-1, MFCD00011721, 10KG
Chem-Impex International, Inc. Choline chloride | 67-48-1 | MFCD00011721 | 1KG
Choline chloride, 67-48-1, MFCD00011721, 1KG
Medchemexpress LLC Benzoylcholine chloride | 2964-09-2 | MFCD00011786 | 98.9% | 243.73 g/mol | C12H18ClNO2 | 10 G
Benzoylcholine chloride is a biochemical reagent used as an organic choline derivative for biochemical assays, synthetic chemistry, and analytical studies in life-science research. Supplied as a solid powder with high purity and well-defined chemical identifiers, it is intended for laboratory research applications only.
- High purity (98.9%) suitable for sensitive biochemical assays.
- Molecular formula C12H18ClNO2 and molecular weight 243.73 g/mol.
- White to almost white powder form for easy handling and dissolution.
- Available in lab-scale sizes (5 g, 10 g, 25 g) for method development.
- Store sealed and away from moisture; short-term cold storage recommendations for solutions.
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Choline tosylate 25g
Choline tosylate is a nucleophilic compound that inhibits phospholipase A2 and phospholipase C Choline tosylate inhibits tumor growth in mice by inhibiting the formation of diacylglycerol (DAG)[1][2]
American Research Products Inc CHOLINE ACETYLTRANSFERASE CHAT
5000264993 CHOLINE ACETYLTRANSFERASE CHAT
Apexbio Technology LLC CHOLIC-ACID-SODIUM-200MG
Cholic acid sodium (CAS No 361-09-1) is a bile acid derivative used extensively in biomedical research Its primary application is in the study of lipid metabolism and liver function Originating from natural bile acids it plays a crucial role in modulating cholesterol homeostasis and fat digestion by activating nuclear receptors such as FXR (Farnesoid X receptor) and influencing the bile acid signaling pathway In vitro it exhibits activity in the nanomolar to low micromolar range demonstrating efficacy in modulating metabolic activities Commonly utilized in hepatocyte cell models animal studies and drug screening assays it aids in understanding pathophysiological mechanisms involved in liver diseases and metabolic disorders Experimental concentrations typically depend on the specific research design allowing for versatility in study applications Its comprehensive role in metabolic research makes it a valuable tool for exploring therapeutic strategies in related fields
Apexbio Technology LLC CHOLINE-BITARTRATE-100MG
Choline bitartrate (CAS No 87-67-2) is a compound widely studied in the field of biomedical research particularly for its role in cellular metabolism and neurotransmission Originating from the combination of choline with bitartrate it enhances the bioavailability of choline in biological systems Its mechanism of action primarily involves serving as a precursor to the neurotransmitter acetylcholine influencing neural pathways and promoting cognitive health In vitro studies typically demonstrate activity in the nanomolar to low micromolar range It is frequently used in cell models and animal studies to investigate its effects on cognitive function and neuroprotection Choline bitartrate is also utilized in drug screening protocols to explore potential therapeutic applications against neurodegenerative diseases Experimental concentrations typically depend on the specific research design with adjustments made according to the study s focus and desired outcomes